Genética molecular

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Las técnicas de genética molecular identifican marcadores de enfermedad de forma temprana, ayudan en el diagnóstico de enfermedades raras/huérfanas y son un componente importante para el seguimiento y propuestas terapéuticas para el manejo de los pacientes con enfermedades oncológicas, raras y/o que tienen una causa molecular.

Los marcadores identificados en el laboratorio de genética molecular, son marcadores muy pequeños, rearreglos de ADN que no son visibles ó detectables mediante otras técnicas, utiliza la PCR (reacción en cadena de la polimerasa) como principal herramienta.

El Servicio de Genética molecular está dirigido a pacientes con enfermedad maligna, enfermedades raras/huérfanas, y sirven para seguimiento ó medir la respuesta a tratamientos.

Consulta las preparaciones para exámenes médicos aquí: http://valledellili.org/atencion-al-paciente/preparacion-para-examenes-medicos/ 

El Laboratorio de Genética molecular de la Fundación Valle del Lili pone a disposición los siguientes servicios:

  • Estudio de quimerismo en sangre completa para seguimiento de trasplante de médula ósea.
  • Estudios de quimerismo de linfocitos B (en pacientes pre y post trasplante, de médula ósea y otros tejidos).
  • Estudios de quimerismo de linfocitos T (en pacientes pre y post trasplante, de médula ósea y otros tejidos).
  • Análisis por PCR  de translocaciones e inversiones en genes de fusión: PCR en tiempo real translocación ABL/BCR (9:22), cuantitativo y cualitativo; PCR en tiempo real translocación PML/RAR [15;17].
  • Estudio inestabilidad microsatélites.
  • PTEN pérdida de heterocigosidad en gliomas (tejido embebido en parafina).
  • Mutaciones JAK2 Janus Quinasa 2 mutación V617F por PCR.
  • Detección de mutaciones en FLT3 y NPM1 para pacientes con leucemia mieloide aguda.
  • Detección de metilación MGMT para tumores de sistema nervioso central.
  • Detección de clonalidad para síndromes linfoproliferativos B y T.

Por qué escoger el Servicio del Laboratorio de Genética molecular de la Fundación Valle del Lili:

  • Personal médico altamente capacitado (dos médicos con maestría y doctorado en  genética de laboratorio y genética clínica).
  • Personal asistencial con entrenamiento especializado en genética molecular.
  • Alto desempeño en las pruebas de control externo de calidad.
  • Trabajo articulado con los grupos clínicos y de patología.
Especialistas en Genética molecular

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