Fundación Valle del Lili’s Haemostasis and Special Hematology laboratory offers the following services:
- Coagulation Abnormalities (Prothrombin time – PT, Activated Partial Thromboplastin Time – aPTT, Thrombin Time TT, Fibrinogen, mixing studies for PT and aPTT.
- Primary Hemostasis – assessment of platelet function by platelet aggregation in a bleeding time study with 4 agonists: ADP, EPN, Collagen, Ristocetin.
- Platelet aggregation for hyperaggregability or thrombosis studies: ADP (2.3, 1.2 – 0.6 uM) – and EPN (11 uM, 1.1 uM, 0.6 uM).
- Platelet aggregation for von Willebrand disease study: RIPA (4 dilutions with Ristocetin: 1.2, 0.6, 0.5, 0.3).
- Platelet aggregation for follow-up of aspirin treatment: arachidonic acid.
- Platelet adhesiveness with Collagen/ADP, Collagen/EPN. Method: PFA-200.
- Secondary hemostasis – bleeding time study – determination of coagulation factor activity: factor II, V, VII, VIII, IX, X, XI.
- Secondary hemostasis – von Willebrand factor antigen, determination of von Willebrand factor activity (ristocetin cofactor).
- Heparin-induced thrombocytopenia (HIT IgG).
- Thrombophilia study: protein C and protein S activity, lupus anticoagulant (Screening and Confirmatory studies).
- Factor V-Leiden Mutation (resistance to activated protein C by PCR).
- G20210A mutation of the prothrombin gene.
- Viscoelastic tests (thromboelastography, platelet mapping (ADP/AA with/without heparinase).
- Monitoring of heparin-anticoagulated patients (UFH and LMWH – anti-Xa factor chromogenic assay for dosage).
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